Petsmile Professional Pet Toothpaste for Cats & Dogs - VOHC Accepted Toothpaste - Clinically Proven to Control Plaque & Tartar…
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Best VOHC-accepted formula
Amazon rating
Amazon aggregate, one input among many in the Verdict Score
Based on 2 trusted sources
Current price
$16.00
Updated Jun 27, 2026 · 1 min read

Sources behind this verdict
10 reviewers weighted by source trust
The consensus
What reviewers found
Synthesized across the trust-weighted source mix below.
Across the reviewers we read, Petsmile occupies a distinct lane: it's the toothpaste people reach for specifically because of its Veterinary Oral Health Council acceptance. The verified vet panel at petmd.com names Petsmile its top dog toothpaste pick, citing an effective formula and palatable flavors, and high-trust r/dogs threads repeatedly describe it as 'the only VOHC approved' paste and a reason owners switched from or supplemented C.E.T. A high-trust r/CatAdvice commenter said their pets tolerate it better than other pastes, and Walmart verified-purchase reviewers report dogs liking the taste enough to permit brushing.
What reviewers liked
- VOHC-accepted with clinically demonstrated plaque/tartar control, a rare independent signal in this category
- Named the top toothpaste pick by the verified vet panel at petmd.com
- Calprox formula is low-abrasive and 'no-brush' friendly per the brand, with widely liked flavors
- High-trust community sentiment is broadly positive across r/dogs and r/CatAdvice
Where it falls short
- Non-enzymatic, which a high-trust r/dogs thread flags as counter to common vet advice
- Smaller retailer review base (4.4 across ~1,925) than the Virbac staples
- The brand itself notes some dogs dislike the smell
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Across the reviewers we read, Petsmile occupies a distinct lane: it's the toothpaste people reach for specifically because of its Veterinary Oral Health Council acceptance. The verified vet panel at petmd.com names Petsmile its top dog toothpaste pick, citing an effective formula and palatable flavors, and high-trust r/dogs threads repeatedly describe it as 'the only VOHC approved' paste and a reason owners switched from or supplemented C.E.T. A high-trust r/CatAdvice commenter said their pets tolerate it better than other pastes, and Walmart verified-purchase reviewers report dogs liking the taste enough to permit brushing.
The disagreement reviewers raise is substantive and worth airing: a high-trust r/dogs thread points out Petsmile is non-enzymatic, which runs counter to the common 'enzymatic is best' advice, prompting some owners to use it alongside an enzyme paste rather than as a sole product. Petsmile's own page also concedes some dogs find the smell unpleasant. The retailer review base is smaller than the Virbac products, so the real-world sample is thinner.
Net, the trust-weighted case is strong because the strongest signal here, an independent VOHC acceptance plus a verified vet-panel endorsement, is exactly the kind of evidence this category often lacks. Owners who prioritize clinically demonstrated plaque/tartar control over the enzymatic mechanism point here.
- #1 Veterinary Dentist Recommended Pet Toothpaste - Petsmile is the VOHC recommended toothpaste for your dogs. The VOHC recognizes that Petsmile meets the highest standards for your pet’s oral health. Using Petsmile toothpaste and brushing daily will significantly improve your pet's dental health!
- Clinically Proven To Prevent Plaque, Tartar & Gingivitis - Petsmile’s proprietary formula Calprox is clinically proven to inhibit plaque and tartar buildup, while whitening teeth by gently dissolving the protein pellicle. Removing the pellicle leaves your pet’s teeth cleaner and whiter while improving gum health and providing kissable fresh breath!
- Pet Safe Human-Grade Ingredients - By using only human-grade ingredients, you can be certain that your pet is using the highest quality pet tooth paste on the market. Your pet can immediately eat or drink after applying Petsmile toothpaste.
- Easy No Brush Toothpaste for Cats & Dogs - The no-brushing required formula makes it easy to improve and maintain even the fussiest pet's oral health. Simply apply Petsmile toothpaste on your cat or dog's teeth and let their tongue do the rest. The great flavor will keep your pet looking forward to their next brushing.
- Clean USA Sourced Formula - Petsmile toothpaste is hypoallergenic and made from only the highest quality ingredients. Veterinary Dentists choose Petsmile because of the high-quality ingredients that promote healthy white teeth and gums. Disclaimer: Our toothpaste never expires. The date on the tube represents the manufacturer date.
Petsmile is the only VOHC approved tooth paste but doesn't seem to have any enzymes. Anything else should add to the arsenal? have two Yorkies.
I use the pet smile one and my cats are ok with it, better than the other toothpastes. It's apparently VOHC accepted too so that's also nice I ...
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“Petsmile Professional Pet Toothpaste Review (We Tried It)” · YouTube
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