Are enzymatic toothpastes safe to swallow?

Most major enzymatic toothpastes are formulated to be swallow-safe (no rinsing required), which is the whole reason they exist for pets. That said, reddit threads flag specific ingredients — notably aloe, neem oil, and grapefruit seed oil in some Vet's Best formulas — as concerns for sensitive dogs. If your dog has allergies or is a puppy, check the ingredient panel and ask your vet.