Can one self-cleaning litter box handle multiple cats?

For two to three average-sized cats, most globe-style and open-top units in this list will keep up if you empty the drawer every 5-10 days. For four or more cats, r/litterrobot moderators and long-term owners consistently recommend either one Litter-Robot per 2-3 cats or stepping up to a larger open-top drum like the Neakasa M1 Plus. Very large breeds (Maine Coons, Ragdolls) are reported to struggle in the smaller globe-style boxes.