Do I need a bread machine with a gluten-free setting?

If you bake gluten-free regularly, yes — gluten-free doughs need a different mix-and-rise profile than wheat doughs, and a dedicated cycle handles that. Most modern machines in this roundup including the Cuisinart CBK-110, KBS Pro, Neretva and the Zojirushi Virtuoso Plus include a gluten-free preset, though reviewers note results still depend heavily on the recipe.