Should I apply clinical antiperspirant at night or in the morning?

Nearly every clinical-strength product in this category is designed to be applied at night on clean, dry skin. Reviewers across r/SkincareAddiction and r/Hyperhidrosis explain that sweat glands are less active overnight, which lets the aluminum salts form the sweat-blocking plug. Several verified-purchase reviewers who applied it in the morning reported irritation and reduced effectiveness.