What is the best adult party card game for large groups?

Cards Against Humanity and the Exploding Kittens Party Pack both scale well to bigger gatherings, with the Exploding Kittens Party Pack explicitly supporting up to 10 players. For a quick, low-setup icebreaker that works across mixed groups, Incohearent is also a strong volume-rated pick. Verified-purchase reviewers consistently favor these three for game nights with six or more people.