What's the difference between a puzzle box and an escape-room-in-a-box?

A traditional puzzle box (often Japanese karakuri-style) has one solution sequence to open it. An escape-room-in-a-box, like the Puzzle Potato Tesla Box, chains multiple distinct puzzles, often combining mechanical and electronic elements, that must be solved in order. r/PuzzleBox consensus is that escape-box formats offer longer play time (5+ hours) but are typically one-and-done unless reset.