Is a vertical mouse or a trackball better for wrist pain?

Reviewers and ergonomics-focused communities frame this as a personal-fit question rather than a clear winner. Vertical mice (like the Logitech Lift and MX Vertical) rotate your wrist into a neutral handshake angle and suit people who want a near-traditional mousing motion, while trackballs (like the Logitech M575S and MX Ergo S) eliminate arm movement entirely and suit cramped desks or shoulder strain. Across the reviewers we read, the strong recommendation is to match the device to your specific pain source and hand size, and to expect an adjustment period of a few days to a couple of weeks.